Fig. 6: Unadjusted and adjusted hazard ratio for all-cause mortality among patients hospitalized after an acute SARS-CoV-2 infection from April 2020 through December 2022 by rurality.

Figure 6 contains Cox Proportional Hazards models for all-cause mortality among patients hospitalized within two weeks (-3/ + 14 days) after an acute SARS-CoV-2 infection by rurality. Deaths are captured from month 0 (day 0) through month 24 (day 730) in the period after diagnosis of COVID-19 at intervals of A) one month, B) three months, C) one year, D) two years, E) two years among patients surviving the initial month after infection, F) two years among patients surviving the initial three months after infection, and G) two years among patients surviving the initial one year after infection. Adjustments were made for sex, age, race/ethnicity, SARS-CoV-2 variant-dominant period at the time of infection, vaccination status, Social Vulnerability Index, U.S. Census Division, and a history of obesity, hypertension, myocardial infarction, congestive heart failure, peripheral vascular disease, rheumatic disease cerebrovascular disease, dementia, chronic pulmonary disease, peptic ulcer disease, hemiplegia or paraplegia, diabetes, liver disease, renal disease, cancer, HIV, tobacco usage, and substance use disorder documented before COVID-19. Forest plots display hazard ratios (points) on a log scale, with horizontal lines representing 95% confidence intervals (error bars). The vertical line indicates the null value of 1.0. Full model specifications are available in Supplementary Data 6.