Table 1 CRISPR screen identifies kinases with inhibitors available
From: RBM39 degrader invigorates innate immunity to eradicate neuroblastoma despite cancer cell plasticity
Groups | Gene | Drug |
|---|---|---|
Shared by naïve, resistant, resistant cultured with indisulam | ATR | Gartisertib |
AURKA | MLN8237 | |
AURKB | AZD2811 | |
CDK7 | Samuraciclib | |
CDK9 | BAY1251152 | |
CHEK1 | LY2880070 | |
PKMYT1 | RP-6306 | |
PLK1 | Onvansertib | |
TTK | CFI-402257 | |
Shared by resistant, and resistant cultured with indisulam | FGFR4 | FGF401 |
CDK2 | PF-07104091 |