Fig. 2: Comparison of transmembrane subunit structures between S. cerevisiae and S. scrofa. | Nature Communications

Fig. 2: Comparison of transmembrane subunit structures between S. cerevisiae and S. scrofa.

From: Cryo-EM structure of the yeast Saccharomyces cerevisiae SDH provides a template for eco-friendly fungicide discovery

Fig. 2

a The alignment of ScSDH with S. scrofa SDH (Type C, PDB ID 1ZOY) in front view and top view. b Demonstration of heme-related amino acids in ScSDH with SsSDH. In SsSDH, D-102His and C-127His interact with heme, while in ScSDH, the allelic amino acids change to D-108Tyr and C-156His. c Top view of ScSDH and SsSDH. SDHC and SDHD alignment with surface representation. Sc, S. cerevisiae; Ss, S. scrofa. All subunits are color-coded. SDHC subunits are colored in green (Sc) and ice blue (Ss); SDHD subunits are colored in orange (Sc) and pink (Ss). PE and Heme are shown as gray stick.

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