Fig. 4: Comparison of analytical sensitivity of malaria detection using spiked whole blood across Dragonfly, Alethia®, DBS-qPCR, and WB-qPCR. Experiments were conducted in collaboration with LSHTM using spiked EDTA-blood with ring-stage P. falciparum 3D7 strain. | Nature Communications

Fig. 4: Comparison of analytical sensitivity of malaria detection using spiked whole blood across Dragonfly, Alethia®, DBS-qPCR, and WB-qPCR. Experiments were conducted in collaboration with LSHTM using spiked EDTA-blood with ring-stage P. falciparum 3D7 strain.

From: Sensitive near point-of-care detection of asymptomatic and submicroscopic Plasmodium falciparum infections in African endemic countries

Fig. 4

Results are shown in terms of a number and percentage of successfully detected replicates at each spike concentration as well as b the resulting empirically determined LOD through probit analysis. The solid curves represent the predicted probabilities of positive results as a function of parasite density, with shaded areas indicating 95% CIs. The red dashed line denotes the LOD or the parasite density at which the probability of a positive result is 95%. Created in BioRender. Cavuto, M. (2025) https://BioRender.com/rwbh4tn. Source data are provided as a Source Data file.

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