Table 1 Clinical and biochemical characteristics of the patients recruited for the sRNA-Seq miR biomarker discovery cohort for miR-190a-5p finding

From: Low circulating miR-190a-5p predicts progression of chronic kidney disease

Variable

Discovery Cohort

 

T2DKD (n = 9)

T2DNRF (n = 13)

NDNRF (n = 11)

p- value

Age (years)

72.7 ± 7.0

69.1 ± 6.9

70.7 ± 7.1

0.503

Sex (male/female)

7/2

8/5

7/4

0.705

SBP (mmHg)

123 ± 10

133 ± 17

138 ± 27

0.244

DBP (mmHg)

68 ± 4

78 ± 10

82 ± 17

0.049

HbA1c (mmol/mol)

61.7 ± 14.2

64.3 ± 18.0

39.5 ± 2.9

0.031

Serum creatinine (µmol/l)

181.1 ± 34.3

80.0 ± 16.1

80.2 ± 15.3

<0.001

eGFR (ml/min/ 1.73 m2)

30.8 ± 7.3

76.9 ± 15.0

77.6 ± 10.1

<0.001

  1. Categorical values were assessed using a Chi-square test. For continuous values with a normal distribution, ANOVA was used to compare 3 groups. T2DKD – type 2 diabetic kidney disease, T2DNRF – type 2 diabetes, normal kidney function, NDNRF – non-diabetic, normal kidney function.
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