Fig. 2: Predicted hydrocarbon oxidation capacity of Ca. ‘Aerovita’ CuMMO.
From: Potential for aerobic hydrocarbon oxidation in archaea
A Maximum-likelihood phylogenetic tree of CuMMO enzymes based on concatenated subunits A, B, and C. Clades are collapsed according to taxonomic class and known substrates in each clade are indicated in parenthesis. Genes indicated in red and green font denote the Ca. ‘Aerovita’ and verified HMO complexes oxidizing hydrocarbon, respectively. Bootstrap values were determined by non-parametric bootstrapping of 100 replicates. Black dots indicate ≥75% bootstrap support and the scale bar represent the number of amino acid substitutions per site. B Predicted HMO trimer complex 3D structure of CM-1. HMO subunits A, B, and C are coloured in red, purple, and green. Predicted copper binding sites based on alphafill are shown in focus with the copper ions depicted as orange-coloured spheres. See Supplementary Data 2 for the quality metrics of transplanted ligands.
