Fig. 3: Overview of the ENCODE functional characterisation experiments.

The figure demonstrates the diversity of ENCODE functional characterisation experiments classified by organism, biosample classification, element selection method and various assays. As evident in the figure, the maximum number of functional characterisation experiments available on the ENCODE portal were performed on Homo sapiens derived cell lines which were assayed using CRISPR screen based assay type. In addition, several reporter based assays are also available from cell line samples originated from Homo sapiens. Moreover, some reporter assays were also performed on human organoids and primary cells. A handful of Mus musculus based functional characterisation experiments are also available from primary cells and cell lines.