Fig. 3: Four possible configurations of Sns and Kirre within the slit diaphragm (SD).
From: The slit diaphragm in Drosophila exhibits a bilayered, fishnet architecture
a Blueprint of the densities observed by cryo-ET. In the middle of the SD, a prominent rhombus with an axis length of ~17 nm and an angle of ~110 degrees can be seen. All relevant dimensions and spacings are indicated. b Kinked arrangement of Sns and Kirre, as observed in the X-ray structure by Özkan et al26. c Stretched arrangement, where Sns and Kirre interact at an angle of 180°. d Four possible molecular configurations based on the fishnet pattern of the SD. Arrows indicate potential interaction interfaces between criss-crossing Ig domains.
