Fig. 3: Induction of memory signaling genes during LTM consolidation.
From: A memory transcriptome time course reveals essential long-term memory transcription factors
A Heatmap indicating pairwise overlap between genes significantly induced in the MB at 7hDT or 1hAT in this time course with MB training-induced genes identified in other previously published datasets27,44 Overlap statistics on each tile connecting two datasets indicate hypergeometric p value for the enrichment, the number of overlapping genes, fold enrichment, and percentage of overlap. B Boxplot displaying z-score normalized expression of 68 core TIGs found in two of three datasets. P values were calculated using a two-sided pairwise t-test. Boxes: 25–75th percentile; center line median; whiskers Tukey (±1.5 × Interquartile Range). C Significant GO terms (FDR < 0.05) for the 68 core TIGs. D Mean z-score normalized expression of core TIGs annotated to GO terms related to G protein-coupled receptor signaling and/or cAMP signaling. Error bars indicate the SEM.
