Table 2 STRATIFY prediction models for Hypotension, Syncope and Fracture. Values represent sub-distribution hazard ratios and 95% confidence intervals

Age

31.06 (29.39–32.81)*

23.54 (22.48–24.65)*

1.03 (1.03–1.03)*

Sex (Female)

0.79 (0.77–0.81)

0.77 (0.75–0.79)

1.59 (1.57–1.62)

Systolic blood pressure

1.53 (1.30–1.80)*

-

1.00 (1.00–1.00)

Black

-

0.98 (0.79–1.23)

0.44 (0.35–0.56)

South Asian

-

0.74 (0.64–0.85)

0.62 (0.55–0.69)

Other

-

0.84 (0.72–0.97)

0.76 (0.68–0.86)

IMD 2

1.06 (1.02–1.1)

1.1 (1.06–1.13)

1.05 (1.03–1.07)

IMD 3

1.11 (1.07–1.15)

1.11 (1.08–1.15)

1.08 (1.05–1.11)

IMD 4

1.21 (1.17–1.25)

1.25 (1.21–1.29)

1.17 (1.14–1.19)

IMD 5 (High)

1.32 (1.27–1.37)

1.43 (1.39–1.47)

1.24 (1.21–1.27)

Underweight

-

-

1.25 (1.19–1.31)

Overweight

-

-

0.84 (0.83–0.86)

Obese

-

-

0.75 (0.73–0.77)

Morbidly obese

-

-

0.66 (0.62–0.70)

Ex-smoker

1.24 (1.2 – 1.27)

-

1.01 (0.99 – 1.03)

Smoker

1.42 (1.37 – 1.47)

-

1.16 (1.13 – 1.18)

Alcohol (ref. Non drinker)

Trivial drinker

0.89 (0.86–0.92)

0.91 (0.88–0.94)

0.97 (0.95–0.99)

Light drinker

0.84 (0.81–0.88)

0.86 (0.83–0.9)

1.02 (0.99–1.05)

Moderate drinker

0.84 (0.80–0.88)

0.86 (0.82–0.89)

1.13 (1.10–1.17)

Heavy drinker

1.29 (1.17–1.43)

1.32 (1.2–1.45)

1.79 (1.68–1.92)

Unknown amount

0.9 (0.86–0.93)

0.92 (0.89–0.95)

1.01 (0.98–1.03)

Dizziness

1.15 (1.11–1.19)

1.15 (1.12–1.18)

-

Dementia

-

0.72 (0.67–0.78)

0.74 (0.71–0.78)

Multiple sclerosis

-

-

1.41 (1.29–1.55)

Hypotension

1.94 (1.83–2.07)

1.32 (1.24–1.42)

-

Syncope

1.4 (1.32–1.49)

2.21 (2.13–2.3)

-

Previous Falls

1.11 (1.07–1.16)

1.18 (1.15–1.21)

1.22 (1.19–1.25)

Previous Fracture

-

-

1.57 (1.54–1.60)

Stroke

1.06 (1.01–1.11)

1.28 (1.23–1.33)

1.06 (1.02–1.10)

Heart failure

-

0.88 (0.83–0.92)

-

Chronic kidney disease

1.46 (1.38–1.55)

-

0.93 (0.89–0.97)

Diabetes

1.27 (1.22–1.31)

1.25 (1.22–1.29)

1.22 (1.18–1.25)

Parkinson’s disease

1.72 (1.62–1.81)

1.17 (1.09–1.26)

1.29 (1.22–1.36)

Spinal cord injury

-

-

-

Ischaemic heart disease

1.21 (1.17–1.24)

1.26 (1.23–1.29)

-

Atrial fibrillation

1.15 (1.1–1.21)

1.06 (1.02–1.11)

Anaemia

1.12 (1.08–1.17)

-

Bradycardia

1.13 (1.01–1.26)

1.12 (0.99–1.27)

-

Tachycardia

1.4 (1.29–1.52)

1.19 (1.1–1.29)

-

Structural cardiac disease

1.22 (1.17–1.27)

1.18 (1.14–1.22)

-

Cardiopulmonary disease

1.31 (1.21–1.42)

1.17 (1.08–1.26)

-

Osteoporosis

-

-

1.30 (1.25–1.34)

Rheumatoid Arthritis

-

-

1.30 (1.24–1.37)

Gastrointestinal Conditions

-

-

1.14 (1.08–1.21)

Epilepsy

-

-

1.37 (1.29–1.46)

Respiratory problems

-

-

1.06 (1.04–1.08)

Chronic liver disease

-

-

1.62 (1.47–1.80)

Antihypertensive drugs

ACE inhibitors

1.41 (1.37–1.45)

1.21 (1.17–1.24)

1.05(1.03–1.07)

Angiotensin II receptor antagonists

1.36 (1.30–1.43)

1.15 (1.1–1.21)

1.04 (1.00–1.07)

Alpha blockers

1.35 (1.26–1.45)

1.24 (1.18–1.31)

1.03 (0.98–1.09)

Beta blockers

1.29 (1.25–1.33)

1.15 (1.12–1.18)

1.00 (0.98–1.02)

Calcium channel blockers

1.19 (1.16 to 1.23)

1.15 (1.12 to 1.18)

1.06 (1.04–1.08)

Diuretics

1.11 (1.07–1.15)

1.15 (1.12–1.17)

1.04 (1.02–1.06)

Other antihypertensives

1.22 (1.13–1.33)

1.08 (1–1.17)

1.14 (1.07–1.21)

Opioids

1.30 (1.27–1.34)

1.19 (1.16–1.23)

1.16 (1.13–1.18)

Hypnotics, anxiolytics

1.07 (1.03–1.11)

1.12 (1.09–1.15)

-

Antipsychotics

-

1.19 (1.13–1.26)

1.12 (1.07–1.17)

Antidepressants

1.31 (1.28–1.35)

1.24 (1.2–1.28)

1.19 (1.16–1.21)

Osteoporosis medications

-

-

1.20 (1.16–1.24)

Systemic corticosteroids

-

-

1.07 (1.04–1.09)

Hormone replacement therapy

-

-

0.76 (0.74–0.78)

Anticonvulsants

-

-

1.37 (1.29 to 1.44)

Proton pump inhibitors

-

-

1.08 (1.06 to 1.10)