Table 4 Regression Estimates From Sex x X-Linked Gene Interactions in the DLPFC with pFDR ≤ 0.10
Outcome | Gene | Analysis | β | SE | T | PFDR |
|---|---|---|---|---|---|---|
Tau Tangles | MCF2 | Sex x MCF2 | 0.28 | 0.07 | 3.74 | 0.052 |
Male-stratified | 0.10 | 0.05 | 1.94 | 0.26 | ||
Female-stratified | −0.18 | 0.06 | −3.33 | 0.02 | ||
HDAC8 | Sex x HDAC8 | −0.30 | 0.08 | −3.82 | 0.052 | |
Male-stratified | −0.08 | 0.05 | −1.60 | 0.37 | ||
Female-stratified | 0.22 | 0.06 | 3.75 | 0.01 | ||
Longitudinal Cognition | SLC10A3 | Sex x SLC10A3 | 0.04 | 0.01 | 3.69 | 0.06 |
Male-stratified | 0.02 | 0.01 | 2.51 | 0.24 | ||
Female-stratified | −0.02 | 0.01 | −2.7. | 0.04 | ||
FTX | Sex x FTX | 0.04 | 0.01 | 3.82 | 0.06 | |
Male-stratified | 0.02 | 0.01 | 3.58 | 0.0496 | ||
Female-stratified | −0.02 | 0.01 | −2.06 | 0.13 |