Fig. 4: H5N1 clade 2.1 serum and nasal wash binding antibodies by group. | Nature Communications

Fig. 4: H5N1 clade 2.1 serum and nasal wash binding antibodies by group.

From: An intranasal adjuvanted, recombinant influenza A/H5 vaccine primes against diverse H5N1 clades: a phase I trial

Fig. 4

A shows the H5 A/Indonesia (Clade 2.1)-specific serum IgG and IgA responses, as well as H5 stalk-specific IgG responses (EU/mL); each dot represents one individual, with summary values shown as geometric mean concentration with 95% confidence intervals. B shows individual nasal wash responses (IgG and IgA) as well as the median and interquartile range of the ratio of H5-specific IgG or IgA (EU/µg) to total IgG or IgA at each timepoint per group. Inset shows nasal wash responses on an extended y-axis. Low-dose (Group A), medium-dose (Group B), and high-dose (Group C) of rH5-NE are shown in maroon, orange, and yellow. Controls, including the unadjuvanted rH5 (Group D) and placebo (Group E), are shown in cyan and gray.

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