Fig. 2: Direct integration of tractography and dissection with BraDiPho. | Nature Communications

Fig. 2: Direct integration of tractography and dissection with BraDiPho.

From: Brain dissection photogrammetry: a tool for studying human white matter connections integrating ex vivo and in vivo multimodal datasets

Fig. 2

Evaluation of the anatomical extent of (A) AG-MFG and (B) AG-SFG connections as reconstructed with in vivo tractography in 39 healthy participants and revealed by ex vivo microdissection of spc-02. The first column illustrates the standard side-by-side comparison between tractography and dissection. The second column shows their direct integration as implemented in BraDiPho. In (A), tractography and dissection evidence of AG–MFG connectivity converge, uncovering fundamental principles of brain organization. In (B), apparent agreement between modalities in the classical side-by-side view is challenged by the integrated BraDiPho approach, which reveals discrepancies in the reconstruction of AG–SFG connections achieved with tractography and dissection. AG angular gyrus, MFG middle frontal gyrus, SFG superior frontal gyrus, spc specimen.

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