Fig. 4: Heatmaps of DISCO. | Nature Communications

Fig. 4: Heatmaps of DISCO.

From: A taxon-specific measurement of disruption in a multi-modal study of microbiomes and metabolomes reveals system-wide dysbiosis preceding HIV-1 infection

Fig. 4: Heatmaps of DISCO.The alternative text for this image may have been generated using AI.

In each panel, species with significant DISCO score in each data modality are denoted by + \(p < 0.01\) and \(q < 0.1\), * \(p < 0.01\) and \(q < 0.05\), ** \(p < 0.01\) and \(q < 0.01\), *** \(p < 0.01\) and \(q < 0.001\). The \(p\)-values are derived from standard Cauchy distribution. The number of correlations for each significant species is more than 20% of maximum correlations in a data modality. For each data modality the top 10 most significant species were selected for graphical representation. A. gut species. B. oral species. MTB-POS and MTB-NEG represent metabolites from positive and negative ion channels, respectively. The sample sizes vary by data modality as described in Supplementary Data 12.

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