Fig. 6: DNAJA2 dysregulation is associated with glucose metabolic disorders. | Nature Communications

Fig. 6: DNAJA2 dysregulation is associated with glucose metabolic disorders.

From: Heat shock protein DNAJA2 controls insulin signaling and glucose homeostasis by preventing spontaneous insulin receptor endocytosis

Fig. 6

A Relative mRNA levels of DNAJA2 in islets from normal and type 2 diabetes mellitus (T2DM) individuals. B Correlations between body mass index (BMI) and DNAJA2 mRNA levels of beta cells in normal individuals and T2DM patients. C Relative mRNA levels of DNAJA2 in blood samples from normal and T2DM individuals. DNAJA2 mRNA levels of islets (D) and adiposes (E) in obese T2DM mice and their lean counterparts. Data are shown as means ± SEM (A, C) or median (D, E). P values were determined by two-tailed unpaired t test with Welch’s correction. *p < 0.05; **p < 0.01; ***p < 0.001, ****p < 0.0001. Source data are provided as a Source Data file.

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