Fig. 1: Schematic illustration of the fabrication of centrifugation-based bioengineered lymphatic tissues (CeLyTs) for lymph node reconstruction. | Nature Communications

Fig. 1: Schematic illustration of the fabrication of centrifugation-based bioengineered lymphatic tissues (CeLyTs) for lymph node reconstruction.

From: Reconstruction of the lymphatic system by transplantation of a centrifuge-based bioengineered lymphatic tissue

Fig. 1

Schematic showing the fabrication of a three-dimensional cellular structure with a lymphatic network composed of LECs and MSCs using a centrifugal cell stacking technique. MSCs, LECs, and MSCs are seeded and layered by centrifugation in that order. The CeLyT is completed by culturing for several days to form a lymphatic network. CeLyTs can survive for a long time after transplantation in LD mice and they form a lymph node-like structure that functions as a lymph node. Figure 1 was created by Science Graphics Inc. (Kyoto, Japan) under a commissioned agreement. All rights have been transferred to the corresponding author.

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