Fig. 6: Therapeutic effect of the transplantation of CeLyTs on lymphedema in LD mice. | Nature Communications

Fig. 6: Therapeutic effect of the transplantation of CeLyTs on lymphedema in LD mice.

From: Reconstruction of the lymphatic system by transplantation of a centrifuge-based bioengineered lymphatic tissue

Fig. 6

a Typical images of the lower limbs of bioengineered tissue-transplanted LD mice. Arrows indicate the measurement site (white, legs; black, paws) in the lower limbs for the evaluation of edema. b,c Change in the size of the paws (b) and legs (c) of bioengineered tissue-transplanted LD mice. The thicknesses of the paws and legs were measured and the change rates from day 0 were calculated. Data represent the mean ± standard deviation from 3 independent experiments, and P-values were determined by two-sided Dunnett’s test. *P < 0.05 was considered statistically significant for the No treatment group. ns, not significant. d Paraffin-section images of the paws of bioengineered tissue-transplanted LD mice (day 21). Arrows indicate the interstitial fluid. Scale bars, 500μm.

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