Fig. 1: Overview of the cohort study and SARS-CoV-2 RNA quantification detected in 32 fetal organs. | Nature Communications

Fig. 1: Overview of the cohort study and SARS-CoV-2 RNA quantification detected in 32 fetal organs.

From: Presence of SARS-CoV-2 in fetal organs via intraamniotic infection

Fig. 1: Overview of the cohort study and SARS-CoV-2 RNA quantification detected in 32 fetal organs.

a Workflow of this study (created with BioRender.com). b Quantification of SARS-CoV-2 RNA in 538 fetal specimens using ddPCR. At the bottom of the figure, the samples were arranged in ascending order based on the duration of infection, from the shortest to the longest, prior to terminating pregnancy. According to the interval between termination and infection, the samples were grouped into early (≤4 weeks; n = 2), mid (≤12 weeks; n = 6) and late (>12 weeks; n = 10) subgroups. The organs were classified according to their respective body systems. ddPCR droplet digital polymerase chain reaction, TEM Transmission electron microscopy, IF Immunofluorescence, HE Hematoxylin and Eosin staining, 4D-DIA Astral-data independent acquisition proteomic, M male, F female. Source data are provided as a Source Data file.

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