Fig. 5: Eigenmode derivation and properties in low and high atrophy subjects.
From: Functional network collapse in neurodegenerative disease
A Procedure for deriving gradient coupling parameters and eigenmodes. B The six eigenmodes for two example subgroups (n = 5) with the lowest or highest total atrophy. Eigenmodes are ordered from lowest to highest frequency. Circle plots show the phase angle and amplitude of each gradient on each eigenmode. Timeseries plots show the resultant gradient oscillations, occurring at the eigenmode-specific frequency. C Eigenmode-based FC matrices for low and high atrophy subjects and the FC difference matrix. VIS visual, SM sensory-motor, DA dorsal attention network, AUD auditory, HIP hippocampal, PHC parahippocampal, AMY amygdala, CO cingulo-opercular, SAL salience, AT anterior temporal, FPl left fronto-parietal, DMN default mode network, FPr right fronto-parietal, SUB subcortical. Portions of A. are reprinted from30 with permission from Elsevier.
