Fig. 5: Comparison of enrichment results from the differential proteins found by high-performing method combinations.
From: Benchmarking informatics workflows for data-independent acquisition single-cell proteomics
a Gene ontology (GO) enrichment results. b Reactome pathway enrichment results. Colors indicate Z-scores of terms. Dot sizes indicate the number of differential proteins. Columns were clustered with Jaccard distances. Mappings of the serial numbers to detailed methods for each step are present in Fig. 2a. The data were processed starting from SR75. Differential analysis was performed between the T2Y1E and C2Y1E sample groups. Differential proteins are determined with p-value < 0.05 and |log2 FC | > log2 1.5.
