Fig. 6: TRACE LFA performance with retrospective and prospective MPXV cohorts.
From: Thermally programmed one-pot CRISPR assay for on-site pandemic surveillance
a TRACE LFA and TRACE results of representative examples of 55 MPXV-positive and 47 MPXV-negative clinical samples stratified by their qPCR CT values and analyzed in parallel (complete results shown in Supplementary Fig. 20), and the sensitivity and specificity estimate of these Ct-stratified groups and the overall cohort. Graphed data depicts the results of single assays performed with clinical samples. b Schematic of MPXV qPCR and TRACE LFA workflows in outpatient clinics. Created in BioRender. Dong, Y. (https://BioRender.com/j2gxvri). c TRACE LFA and central laboratory qPCR test results for 28 outpatients evaluated for suspected MPXV infections (details shown in Supplementary Fig. 21). Source data are provided as a Source Data file.
