Table 1 Participant characteristics
Characteristic | Overall | BA.1 wave | BA.2 wave |
|---|---|---|---|
Participants – N | 345 | 251 | 94 |
Households – N | 91a | 66 | 32 |
Participants per household – Median (IQR) | 3 (2, 5) | 3 (2, 5) | 3 (2, 3) |
Age – Median (IQR) | 18 (9, 40) | 18 (9, 39) | 17 (10, 41) |
Female sex – N (%) | 211 (61%) | 151 (60%) | 60 (64%) |
Infected – N (%) | 194 (56%) | 153 (61%) | 41 (44%) |
Infection severity – N (%) | |||
Subclinical | 89 (46%) | 77 (50%) | 12 (29%) |
Mild | 78 (40%) | 52 (34%) | 26 (63%) |
Moderate | 24 (12%) | 21 (14%) | 3 (7.3%) |
Severe | 3 (1.5%) | 3 (2.0%) | 0 (0%) |
Infection history – N (%) | |||
No prior infections | 23 (6.7%) | 18 (7.2%) | 5 (5.3%) |
1 prior infection | 235 (68%) | 171 (68%) | 64 (68%) |
2 prior infections | 80 (23%) | 58 (23%) | 22 (23%) |
3 prior infections | 7 (2.0%) | 4 (1.6%) | 3 (3.2%) |
Time since last infection – Median (IQR) | 406 (163, 584) | 380 (150, 580) | 437 (263, 689) |
Vaccination history | |||
Unvaccinated | 112 (32%) | 90 (36%) | 22 (23%) |
1 prior dose | 71 (21%) | 59 (24%) | 12 (13%) |
2 prior doses | 75 (22%) | 57 (23%) | 18 (19%) |
>2 prior doses | 87 (25%) | 45 (18%) | 42 (45%) |
Time since last Vax dose – Median (IQR) | 77 (34, 102) | 62 (22, 93) | 112 (77, 162) |
Pre-infection titers – Median (IQR) | |||
Neut BA.1 ID50 | 1347 (180, 3330) | 1061 (146, 3130) | 1839 (554, 3943) |
Neut BA.2 ID50 | 1482 (292, 4517) | 1332 (218, 3975) | 2150 (709, 5338) |
Neut DG14G ID50 | 5038 (1315, 11694) | 4798 (1173, 12509) | 5132 (1954, 10882) |
Spike ELISA titer | 8553 (2198, 28937) | 7166 (1505, 26138)b | 10660 (5168, 36256) |
Sample time before infection (Neut)c – Median (IQR) | −4 (−17, 0) | −4 (−14, 0) | −3 (−22, 0) |
Sample time before infection (Spike)c – Median (IQR) | −6 (−60, 0) | −6 (−67, 0)b | −6 (−60, 0) |
