Fig. 3: Association between selection for MHC I diversity and adult body mass, adult life expectancy or 80% adult longevity.
From: Immunological surveillance against cancer across mammals
Selection for MHC I diversity a–c overall or c–e at the 20 most positively selected sites (PSS) in function of a, d adult body mass, b, e adult life expectancy, or c, f 80% adult longevity. Associations were tested using phylogenetic generalized least squares regressions. Models shown in (b, c, e, f) were weighted for (and points are proportional to) the precision of life expectancy and 80% adult longevity estimates (reflected by the log number of individuals with RDI). Slopes originate from phylogenetic regressions presented in Table S8. Selection for MHC I diversity only increased with 80% adult longevity (p = 0.0051). All statistical tests performed are two-sided and no correction for multiple testing was performed.
