Fig. 2: MLS-associated alternative splicing events in mammals.
From: The implications of alternative splicing regulation for maximum lifespan
Bar plots illustrate the number of AS events where the percent spliced-in (PSI) level is positively (a) or negatively (b) correlated with MLS, body mass (BM), or both. Jaccard index values are calculated to show the similarity between BM-associated and MLS-associated AS events for (c) positive association, and (d) negative association. This index is determined by dividing the overlap of AS events between MLS-associated and BM-associated AS by the size of the union of MLS-associated and BM-associated AS events. Similarity between BM-associated and MLS-associated genes is calculated for (e) positive association and (f) negative association.
