Fig. 5: Hippocampal synaptic types are mostly defined by genes regulating neurotransmitter receptor function. | Nature Communications

Fig. 5: Hippocampal synaptic types are mostly defined by genes regulating neurotransmitter receptor function.

From: Synaptic proteome diversity is shaped by the levels of glutamate receptors and their regulatory proteins

Fig. 5: Hippocampal synaptic types are mostly defined by genes regulating neurotransmitter receptor function.

a ABCA taxonomy tree of neuronal types (left). Those types with upregulated synaptic genes that retrieve enriched signaling pathways are shown in the right with solid lines. Dashed lines correspond to neuron types whose upregulated genes cannot be linked to a significantly overexpressed term. These synapses would not present any functional difference from those of other neurons from the same class. b Fold enrichment of significantly enriched terms related to neurotransmitter receptor function (blue bars) or synaptic vesicle exocytosis (red bars). Dark blue or red denotes a term that is the most enriched one for that synaptic type. Light colors denote terms that are enriched but are not the most enriched. Fold enrichment corresponds to the ratio between the number of observed and expected genes related to one term.

Back to article page