Fig. 3: Gene copy number variations between the parental and pressure 4 strains. | Nature Communications

Fig. 3: Gene copy number variations between the parental and pressure 4 strains.

From: Tolerance of Plasmodium falciparum mefloquine-resistant clinical isolates to mefloquine-piperaquine with implications for triple artemisinin-based combination therapies

Fig. 3: Gene copy number variations between the parental and pressure 4 strains.

Each dot represents a gene. Green and red dots indicate genes that are amplified (ratio ≥1.5) or deleted (ratio ≤0.5) in the Pressure 4 strain, respectively. Grey dots show genes with relatively stable copy numbers. pfmdr1, pfpm2 and pfpm3, which have previously been associated with drug resistance, are labeled. The complete list of amplified and deleted genes in the Pressure 4 strain is provided in Supplementary Table 2. Source data are provided as a Source Data file.

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