Fig. 3: The lineage hierarchy of incisor mesenchyme is established between E14.5 and E16.5. | Nature Communications

Fig. 3: The lineage hierarchy of incisor mesenchyme is established between E14.5 and E16.5.

From: Autocrine ECM molecules establish MSC quiescence during incisor development by disrupting WNT ligand trafficking process

Fig. 3: The lineage hierarchy of incisor mesenchyme is established between E14.5 and E16.5.The alternative text for this image may have been generated using AI.

a UMAP plots of the incisor mesenchyme at E13.5, E14.5, E15.5, E16.5, E18.5 and P56. b Heatmap of signature genes in the incisor mesenchyme at E14.5, E16.5, E18.5, and P56. c–v Mip-seq analysis of signature genes in the incisor mesenchyme at E14.5, E16.5, E18.5, and P56. White arrows indicate regions with signals. White dotted lines outline the dental epithelium. Scale bars: 100 μm. Representative images from three independent experiments with similar results. w Dotplot visualizing representative genes in each cell cluster of incisor mesenchyme at E14.5, E16.5, E18.5, and P56.

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