Table 1 Characteristics of Indigenous and non-Indigenous subjects

From: Indigenous infants in remote Australia retain an ancestral gut microbiome despite encroaching Westernization

 

Indigenous

Non- Indigenous

P valuea

Sex: female, male

24, 26

24, 26

 

Age (days)

 Median (IQR)

331 (166, 462)

332 (175, 458)

0.958

 Mean (SD)

317 (170)

317 (171)

 

Gestational age at delivery (weeks)

 Median (IQR)

38.0 (37.0,39.0)

38.0 (37.3, 39.4)

0.200

 Mean (SD)

37.6 (2.82)

38.2 (1.63)

 

Mode of delivery

 Vaginal

32/50 (64%)

26/50 (52%)

0.311

 Cesarean section (elective)

11/50 (22%)

13/50 (26%)

0.815

 Cesarean section (emergency)

7/50 (14%)

11/50 (22%)

0.436

Intrapartum antibiotics

   

 Vaginal

Unknown

15/26 (58%)

 

 Cesarean section (elective)

12/13 (92%)

 

 Cesarean section (emergency)

11/11 (100%)

 

Birth weight (Kg)

   

 Median (IQR)

3.15 (2.77,3.37)

3.53 (3.15, 3.86)

0.0004

 Mean (SD)

3.09 (0.614)

3.52 (0.552)

 

Breastfeeding

   

 Current

47/50 (94%)

24/50 (48%)

<0.0001

 Exclusive for the first 6 months

42/50 (84%)

3/50 (6%)

<0.0001

Complementary food started (months)

   

 Median (IQR)

5.00 (4.50, 6.00)

4.60 (4.37, 5.52)

0.006

 Mean (SD)

5.46 (1.38)

4.80 (0.924)

 

Maternal body mass index (BMI)b

   

 Median (IQR)

22.6 (18.6,25.8)

25.2 (21.9,30.7)

<0.0001

 Mean (SD)

22.7 (4.9)

26.3 (4.9)

 

Consumption of traditional foods by the mother, at least twice weekly

46/50 (92%)

Not applicable

 

Number of people living in the home

   

 Median (IQR)

4.00 (3.00, 7.25)

4.00 (3.00, 4.75)

0.017

 Mean (SD)

6.70 (8.14)

3.87 (1.13)

 

At least one furred animal in the household

25/50

30/50

0.422

Type 1 diabetes proband

   

 Father

0

12/50 (24%)

 

 Mother

0

27/50 (54%)

 

 Sibling

0

10/50 (20%)

 

Fecal calprotectin (normal 100 mg/g)

   

 Median (IQR)

1318 (515, 1809)

39.9 (4.40, 102)

<0.0001

 Mean (SD)

1274 (734)

71.5 (103)

 

Serum intestinal fatty acid binding protein (normal <1664 pg/ml)

   

 Median (IQR)

637 (419–1091)

689 (517–1572)

0.538

 Mean (SD)

954 (962)

1062 (777)

 

Fecal parasites by microscopy

15/50 (30%)

Not determined

 

Antibiotic (amoxycillin in the majority) within 1 month of fecal collection

5 (10%)

8 (16%)

0.554

Any antibiotic ever

Unknown

11/50 (22%)

 
  1. aUnpaired t-test (two-tailed) or Fisher’s Exact test for categorical variables.
  2. bIndigenous was post-pregnancy when the infant was assessed; non-Indigenous was pre-pregnancy.