Fig. 5: Genetic correlation between 25OHD and selected traits. | Nature Communications

Fig. 5: Genetic correlation between 25OHD and selected traits.

From: Genome-wide gene-environment interaction study uncovers 162 vitamin D status variants using a precise ambient UVB measure

Fig. 5: Genetic correlation between 25OHD and selected traits.

Genetic correlation between 25OHD, based on marginal effects, and 25 publicly available GWAS traits. Traits were selected if they have been previously studied in relation to vitamin D status. Genetic correlation (rg) between 25OHD and the phenotype is on the x-axis and the −log10(p-value) of the association is on the y-axis (rg > 0 shown in green, rg < 0 in purple). The horizontal line represents the Bonferroni-corrected significance threshold (0.05/21) and the vertical line represents rg = 0. CRC colorectal cancer, SBP systolic blood pressure, DBP diastolic blood pressure, CAD coronary artery disease.

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