Fig. 1: hTRPV6 function at different concentrations of intracellular Mg2+.
From: The locking mechanism of human TRPV6 inhibition by intracellular magnesium
a Voltage ramp protocol. b Average voltage dependence of whole-cell currents (mean ± SEM) recorded from hTRPV6-expressing HEK293 cells in the absence (black) or presence of 2 mM intracellular Mg2+ (blue) using the protocol shown in (a). c Voltage step protocol. d Representative whole-cell currents recorded in the absence (black) or presence of 2 mM intracellular Mg2+ (blue) using the protocol illustrated in (c) for the step from –100 to +40 mV. e Average voltage dependence of whole-cell currents (mean ± SEM) measured at the time point of 199 ms using the protocol in (c). n is the number of cells examined.
