Table 1 Risk of incident coronary heart disease according to the categories of the eight domains
Domains | n/N | HR | p value | p for trend |
|---|---|---|---|---|
Socioeconomic status | ||||
Favorable | 6905/136,714 | 1.00 (Reference) | - | |
Intermediate | 9399/140,380 | 1.06 (1.03, 1.09) | 3.57 × 10−04 | 1.04 × 10−32 |
Unfavorable | 11,288/117,485 | 1.21 (1.17, 1.26) | 1.52 × 10−29 | |
Lifestyles | ||||
Favorable | 6828/131,527 | 1.00 (Reference) | - | |
Intermediate | 8717/131,526 | 1.11 (1.07, 1.15) | 2.35 × 10−10 | 1.80 × 10−72 |
Unfavorable | 12,047/131,526 | 1.33 (1.29, 1.37) | 6.93 × 10−66 | |
Early life factors | ||||
Favorable | 9013/132,366 | 1.00 (Reference) | - | |
Intermediate | 9267/132,742 | 1.00 (0.97, 1.03) | 9.96 × 10−01 | 6.61×10−03 |
Unfavorable | 9312 /129,471 | 1.04 (1.01, 1.07) | 1.05 × 10−02 | |
Psychosocial factors | ||||
Favorable | 7701/131,538 | 1.00 (Reference) | - | |
Intermediate | 9056/131,668 | 0.98 (0.95, 1.01) | 1.25 × 10−01 | 5.47 × 10−06 |
Unfavorable | 10,835/131,373 | 1.06 (1.03, 1.10) | 8.43 × 10−05 | |
Local environment | ||||
Favorable | 8899/132,918 | 1.00 (Reference) | - | |
Intermediate | 9515/130,137 | 1.05 (1.01, 1.08) | 3.58 × 10−03 | 1.66 × 10−02 |
Unfavorable | 9178/131,524 | 1.04 (1.00, 1.07) | 2.96 × 10−02 | |
Blood assays | ||||
Favorable | 5010/131,527 | 1.00 (Reference) | - | |
Intermediate | 8213/131,526 | 1.20 (1.16, 1.25) | 2.68 × 10−24 | 1.53 × 10−205 |
Unfavorable | 14,369/131,526 | 1.65 (1.59, 1.70) | 2.41 × 10−177 | |
Physical measures | ||||
Favorable | 7210/131,527 | 1.00 (Reference) | - | |
Intermediate | 8686/132,932 | 1.11 (1.07, 1.14) | 1.81 × 10−09 | 4.89 × 10−62 |
Unfavorable | 11,696/130,120 | 1.34 (1.29, 1.39) | 1.81 × 10−58 | |
Health and medical history | ||||
Favorable | 5512/131,836 | 1.00 (Reference) | - | |
Intermediate | 7858/131,217 | 1.24 (1.20, 1.28) | 6.89 × 10−33 | 1.03 × 10−267 |
Unfavorable | 14,222/131,526 | 1.78 (1.72, 1.84) | 7.78 × 10−239 |