Fig. 8: Prevotella stercorea abundance increases with age while illness susceptibility peaks in toddlers.
From: Gut Prevotella stercorea associates with protection against infection in rural African children
A P. stercorea abundance across age groups. Boxplot of P. stercorea abundance at D85 across age groups (7–12 months, n = 88; 1–2 years, n = 282; >2 years, n = 263). Boxes show medians, interquartile ranges (IQR), minima and maxima, with whiskers extending to 1.5 × IQR; points represent biological replicates. Two-sided ANOVA showed a significant age-associated increase (F(2, 1373) = 49.41, p = 1.90 × 10⁻²¹). Post hoc Tukey HSD comparisons: 1–2 versus 7–12 months (difference = 1.63, p = 6.94 × 10⁻¹⁰); >2 versus 7–12 months (difference = 2.53, p < 1 × 10⁻²⁰); >2 versus 1–2 years (difference = 0.90, p = 1.84 × 10⁻⁶). Logistic regression testing for an interaction between P. stercorea abundance and age in predicting illness showed no significant interaction (p = 0.757). B Illness prevalence peaks in toddlers. Bar plot shows illness (AE) status peaking in the 1–2 year age group: 7–12 months (Ill, n = 59; Not-Ill, n = 29); 1–2 years (Ill, n = 201; Not-Ill, n = 80); >2 years (Ill, n = 158; Not-Ill, n = 101); χ² = 22.69, d.f. = 2, p = 1.19 × 10⁻⁵.
