Fig. 4: PKMDR-FLIM maps MMP heterogeneity from cell to tissues.
From: Imaging mitochondrial membrane potential via concentration-dependent fluorescence lifetime changes
a Intensity and FLIM images of PKMDR-stained mitochondria and nucleus (intensity images, grey) in brain organoid and tumor slice. b Bright field, intensity and FLIM images of TMRM- and PKMDR-stained mitochondria in mouse 2-cell, 4-cells, 8-cells embryos, morula and blastocyst. Schematic illustration of samples imaged in this figure. c Bar plots showing the average mitochondrial fluorescence lifetime in each cell (n = 3 samples). Scale bar = 20 μm. Data were presented as the mean ± SEM.
