Fig. 1: Cell type and brain region identification in young adult mouse brain by MERFISH. | Nature Communications

Fig. 1: Cell type and brain region identification in young adult mouse brain by MERFISH.

From: A spatial atlas of the complement system uncovers unique expression patterns in postnatal brain development in mice

Fig. 1: Cell type and brain region identification in young adult mouse brain by MERFISH.

A UMAP visualization of primary cell clusters identified by MERFISH in p60 mouse brain sagittal sections. B The spatial localization of each primary cell type in a representative brain slice. Cells are colored by cell type as in (A). C The spatial location of identified brain regions for the slice in (B). Spatial localization of secondary cell clusters of vGlut1+ (ExN-vGlut1, D) and vGlut2+ (ExN-vGlut2, E) excitatory neurons, inhibitory neurons (InN, F), astrocytes (Astro, G), oligodendrocytes (OD, H), microglia (MG, I), oligodendrocyte progenitor cells (OPC, J) and endothelial cells (Endo, K) for the slice in (B). Full lists of cell type and brain region abbreviations can be found in Tables S2 and S3, respectively. Note that PF (parafascicular region) and RT (reticular nucleus) are thalamic nuclei, and that Th designates other thalamic regions that are not further distinguished. Scale bar: 2 mm. Source data are deposited on Data Dryad (https://doi.org/10.5061/dryad.cnp5hqcbq).

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