Fig. 1: Cryo-EM maps and models of the YenTc holotoxin in both prepore and pore conformation. | Nature Communications

Fig. 1: Cryo-EM maps and models of the YenTc holotoxin in both prepore and pore conformation.

From: Complete structures of the YenTc holotoxin prepore and pore reveal the evolutionary basis for chitinase incorporation into ABC toxins

Fig. 1: Cryo-EM maps and models of the YenTc holotoxin in both prepore and pore conformation.

CryoEM map of the prepore (A) and pore (C) holotoxin structure showing the side (top) and top (bottom) views. Each protomer is shown in a different colour. B, D YenTc holotoxin protomer showing YenA1, YenA2, Chi2 and Chi1. The domains and subunits of the protomer are represented by different colours: Orange: YenA1 α-helical shell domain, red: YenA2 α-helical shell domain, dark green: TcB-binding domain, grey: α-helical pore domain, light green: linker, dark blue: neuraminidase-like domain, pink: chitinase-binding domain A (CBD-A), blue-green: Chi2 chitinase, pale green: chitinase-binding domain B (CBD-B), purple: Chi1 chitinase.

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