Fig. 4: Synthesis of hapmnioide A (1) and haploide O (2). | Nature Communications

Fig. 4: Synthesis of hapmnioide A (1) and haploide O (2).

From: Divergent synthesis of Haplomitrium diterpenoids via a late-stage biomimetic skeletal reorganization approach

Fig. 4: Synthesis of hapmnioide A (1) and haploide O (2).The alternative text for this image may have been generated using AI.

a Divergent total synthesis of hapmnioide A (1) and haploide O (2) from the common intermediate 8. b Optimization of reaction conditions for pivotal 1,2-acyl migration. TBAF tetrabutylammonium fluoride, KHMDS potassium bis(trimethylsilyl)amide, rt room temperature.

Back to article page