Table 6 List of Risk Factors and multivariate model parameters
Risk Factors | Multivariate model confounders |
|---|---|
Age | Age |
Sex | Sex |
Site of acquisition | Site of acquisition (healthcare-associated Vs nosocomial) |
Solid cancer | |
Hematological malignancy | Solid cancer |
Biliary disease | Hematological malignancy |
Neurological disorder | Biliary disease |
Diabetes mellitus | Neurological disorder |
Hypertension | Diabetes mellitus |
Alcohol use disorder | Hypertension |
Chronic renal failure | Alcohol use disorder |
End-stage renal disease | Chronic renal failure |
Liver cirrhosis | End-stage renal disease |
Solid organ transplantation | Liver cirrhosis |
Haematopoietic stem cell transplantation | Solid organ transplantation |
COPD or bronchiectasis | Haematopoietic stem cell transplantation |
Rheumatological disease | COPD or bronchiectasis |
Ischemic heart disease | Rheumatologic disease |
Heart failure | Ischemic heart disease |
Neutropenia | Heart failure |
Recent surgery | McCabe score |
Chemotherapy | Charlson index |
Immunosuppressive therapy | Neutropenia |
Sepsis grade | Recent surgery |
Site of infection | Chemotherapy |
Previous anti-MRSA therapy | Mucositis |
Previous VAN use | Immunosuppressive therapy |
VAN MIC by BMD | ICU care |
Interaction: age × sex | Previous anti-MRSA therapy |
Previous vancomycin exposure | |
Vancomycin MIC by BMD | |