Fig. 5: Metabolic similarity and structural connectivity. | Nature Communications

Fig. 5: Metabolic similarity and structural connectivity.

From: Constructing the human brain metabolic connectome with MR spectroscopic imaging reveals cerebral biochemical organization

Fig. 5: Metabolic similarity and structural connectivity.

a Example individual metabolic similarity (MetSiM) and structural connectivity (SC; fiber density) matrices. b Edge-wise correlation between SC and MetSiM as a function of structural order \({{\mathscr{O}}}(n)\) (paths with n − 1 intermediary nodes). Points show the mean Pearson correlation across participants (n = 42); shaded bands indicate 95% confidence intervals. Two-sided tests used one-sample t-tests on Fisher-z transformed correlations against zero. c Correlation between the communicability model \(M=\exp (gS)\) and the observed MetSiM. Curves show the mean Pearson correlation across participants with 95% confidence intervals; two-sided one-sample t-tests on Fisher-z values assessed deviation from zero. d First uniform manifold approximation and projection (UMAP) component of group average connectivity matrix from the Geneva study.

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