Fig. 7: Metabolic Similarity and Cytoarchitectural Similarity.

a Cytoarchitectonic classification of cortical laminar patterns performed by Seidlitz et al.35 (left) and based on the Cognitive-Consilience dataset41 and classification of metabolically similar cortical regions based. b Von Economo cytoarchitectural similarity matrix, its corresponding absolute nodal correlation with the group MetSiM (p < 0.05; AdjPerm) (top) and its first PCA/t-SNE component (bottom). c BigBrain cytoarchitectural similarity matrix and its corresponding absolute nodal correlation with the group MetSiM (p < 0.05; AdjPerm) (top) and its first PCA/t-SNE component (bottom). Statistics (b,c). Global and nodal associations were tested with two-sided Spearman rank correlations. Significance was derived from 10000 permutations; adjusted permutation p-values are reported as AdjPerm.