Fig. 5: Three genes upregulated due to an intronic enKoRV. | Nature Communications

Fig. 5: Three genes upregulated due to an intronic enKoRV.

From: Multi-generational koala pedigree analysis reveals rapid changes in heritable provirus load associated with life history traits

Fig. 5: Three genes upregulated due to an intronic enKoRV.

a Sequence of the koala reference genome, Bilbo, for the SLC29A1 gene containing an enKoRV in the intron region. b Sequence of the LONP2 gene containing an enKoRV-A integration in an intron region, mapped to the contigs of PacBio long-reads assembled from an EUZ koala. c Sequence of the STAP1 gene containing an enKoRV-A integration in an intron region, mapped to the contigs of PacBio long-reads assembled from an EUZ koala. On the right side of each alignment sequence, a boxplot shows the gene count normalized by sequencing depth in animals containing the enKoRV versus the normalized gene count in animals without the enKoRV. Boxplots show the median, the 25–75th percentiles in the box, and whiskers to 1.5× IQR (interquartile range). A significant p-value of a two-side Mann-Whitney test comparing the two groups is shown above the plots. Source data are provided as a Source Data file.

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