Table 1 Main Sample sociodemographics
From: Vulnerability to memory decline in aging revealed by a mega-analysis of structural brain change
Dataset | Subjects | Apoe ε4 | Age | Obs. Memory | Obs. Brain | Time Brain | Time Memory | ||
|---|---|---|---|---|---|---|---|---|---|
N (m) | NC:C | M (SD) range | N | M (SD) range | N | M (SD) range | M (SD) range | M (SD) range | |
adni | 223 (92) | 158:65 | 72.4 (6.3) | 1118 | 5.0 (2.7) | 984 | 4.4 (2.2) | 3.9 (2.1) | 4.6 (2.8) |
55.8–89.9 | 2–13 | 2–12 | 1.6–9.6 | 2.0–13.5 | |||||
aibl | 142 (70) | 94:78 | 71.5 (6.4) | 564 | 4.0 (1.1) | 493 | 3.5 (1.1) | 4.2 (1.6) | 4.9 (1.6) |
60.0–87.0 | 2–5 | 2–5 | 2.0–8.0 | 2.0–7.0 | |||||
base-ii | 214 (127) | 133:39 | 64.8 (15.0) | 572 | 2.7 (0.5) | 428 | 2.0 (0) | 2.3 (0.4) | 4.5 (1.5) |
24.5–83.1 | 2–3 | 2–2 | 1.5–3.1 | 1.6–6.4 | |||||
bbhi | 256 (141) | 30:3 | 54.0 (7.2) | 512 | 2.0 (0) | 512 | 2.0 (0) | 2.4 (0.2) | 2.4 (0.2) |
41.2–66.1 | 2–2 | 2–2 | 1.6–3.0 | 1.6–3.0 | |||||
betula | 47 (27) | 26:15 | 43.8 (12.8) | 94 | 2.0 (0) | 94 | 2.0 (0) | 4.3 (0.4) | 4.3 (0.4) |
25.0–75.0 | 2–2 | 2–2 | 4.0–5.0 | 4.0–5.0 | |||||
cognorm | 93 (42) | 54:38 | 73.2 (6.0) | 596 | 6.4 (1.0) | 366 | 3.9 (1.3) | 6.0 (2.6) | 5.8 (0.9) |
64.7–90.0 | 3–7 | 2–6 | 1.8–9.5 | 2.1–6.9 | |||||
habs | 223 (94) | 157:63 | 73.3 (6.1) | 1180 | 5.3 (1.0) | 615 | 2.8 (0.6) | 4.4 (1.2) | 4.5 (1.1) |
62.5–89.3 | 3–6 | 2–4 | 2.0–8.5 | 2.0–8.5 | |||||
lcbc | 304 (120) | 100:72 | 47.9 (19.1) | 781 | 2.6 (0.7) | 799 | 2.6 (0.8) | 6.2 (2.8) | 6.0 (2.7) |
20.0–85.5 | 2–4 | 2–7 | 2.4–11.5 | 2.4–11.5 | |||||
oasis3 | 431 (171) | 287:137 | 67.2 (8.9) | 3502 | 8.1 (4.0) | 1458 | 3.4 (1.5) | 6.4 (3.4) | 9.9 (4.2) |
43.5–95.6 | 2–23 | 2–8 | 1.5–15.8 | 2.0–24.0 | |||||
preventad | 184 (53) | 115:69 | 63.6 (5.0) | 874 | 4.8 (1.0) | 1061 | 5.8 (1.0) | 3.3 (0.8) | 3.2 (0.8) |
55.1–83.3 | 3–6 | 4–7 | 1.9–4.7 | 1.6–4.5 | |||||
Ub | 77 (28) | 67:10 | 68.6 (5.0) | 214 | 2.8 (0.4) | 208 | 2.7 (0.5) | 3.5 (1.0) | 3.7 (1.0) |
51.7–78.1 | 2–3 | 2–3 | 1.6–5.0 | 1.6–5.2 | |||||
Ukb | 1066 (525) | 775:272 | 62.3 (7.0) | 2132 | 2.0 (0) | 2132 | 2.0 (0) | 2.3 (0.1) | 2.3 (0.1) |
47.0–79.5 | 2–2 | 2–2 | 2.0–2.7 | 2.0–2.7 | |||||
vetsa | 477 (477) | 354:122 | 58.0 (3.9) | 1321 | 2.8 (0.4) | 1193 | 2.5 (0.5) | 9.3 (2.7) | 10.0 (2.4) |
51.1–70.1 | 2–3 | 2–3 | 4.5–13.4 | 4.5–14.4 | |||||
All | 3737 (1967) | 2350:953 | 62.5 (11.6) | 13460 | 3.6 (2.6) | 10343 | 2.8 (1.3) | 4.5 (3.0) | 5.1 (3.6) |
20.1–95.6 | 2–23 | 2–12 | 1.5–15.8 | 1.6–24.0 | |||||