Fig. 9: Schematic model for H3K36me-mediated epigenome integrity.
From: H3K36 Methylation as a Guardian of Epigenome Integrity

H3K36 methylation prevents the invasion of PRC2-mediated H3K27me3 and SUV39H1-mediated H3K9me3 into euchromatin and is essential for maintaining the segregation of euchromatin and heterochromatin as well as overall genome compartmentalization. Created in BioRender. Shipman, G. (2025) https://BioRender.com/0iz7mrr.