Fig. 1: Study design, microbial diversity, and taxonomic composition of maternal milk and infant stool microbiomes over time.
From: Assembly of the infant gut microbiome and resistome are linked to bacterial strains in mother’s milk
A Study design overview for the 507 samples collected from 195 mother-infant pairs. Infant stool samples (n = 334) were collected at one (1 M) and six months (6 M) of life. Maternal breast milk samples (n = 173) were collected one and three months (3 M) after delivery. B Shannon diversity distribution for infant stool and maternal milk samples over time. P-values calculated using two-sided paired t-test (* for p ≤ 0.05, ** for p ≤ 0.01 and **** for p ≤ 0.0001). Samples included: 122 for milk at one month, 25 for milk three months, 175 for stool one month and 159 for stool at six months of age. Taxonomic composition of (C) the most prevalent and abundant species found in the human breast milk and (D) in the infant gut microbiome samples in relation to sample collection time point, predominance group and other relevant infant metadata. The predominance group identifies the most abundant species in each sample. Ordination plot based on Bray-Curtis distance between samples for PCoA1 and PCoA2 (E) and PCoA1 and PCoA3 (F), colored by body site of origin and sampling time. Percentage of variance explained (PVE) is reported in parentheses.
