Fig. 6: Culture collection to study biofilms from peri-implantitis.

Number of reference species, reference strains, peri-implantitis isolate species and peri-implantitis isolate strains is plotted in the top panel for clinically relevant genera. Reference strains were obtained from other culture collections to cover microbial diversity in peri-implantitis and were used to develop and validate laser-assisted culturomics. Strains from peri-implantitis were isolated in this study. Relative transcriptional activity of genera in peri-implantitis biofilms (n = 31, displayed as boxplots with 95% CI, with ‘o’ and ‘*‘ denoting mild and extreme outliers, respectively) was retrieved from previous study⁴³ and plotted in a bottom panel. Top 50 taxa were sorted by decreasing activity and colored by class. Detailed information can be found in Supplementary Data 7 and in the Source Data.