Table 4 Severity of vaccine-related adverse events reported within 28 days

From: Immunogenicity and safety of co-purified diphtheria, tetanus and acellular pertussis vaccine in 6-year-old Chinese children

Adverse events

co-purified DTaP (N = 240)

DT (N = 240)

P

Total, n (%)

 Grade 1

49 (20.42)

18 (7.50)

< 0.001

 Grade 2

41 (17.08)

10 (4.17)

< 0.001

 ≥ Grade 3

2 (0.83)

0 (0)

0.499

Systemic, n (%)

 Grade 1

6 (2.50)

1 (0.42)

0.122

 Grade 2

8 (3.33)

5 (2.08)

0.399

 ≥ Grade 3

1 (0.42)

0 (0)

> 0.999

Local, n (%)

 Grade 1

45 (18.75)

16 (6.67)

< 0.001

 Grade 2

36 (15.00)

5 (2.08)

< 0.001

 ≥ Grade 3

1 (0.42)

0 (0)

> 0.999

  1. Adverse events were compared between arms using the two-sided χ2 test or Fisher’s exact test. co-purified DTaP, co-purified diphtheria, tetanus and acellular pertussis combined vaccine; DT, diphtheria and tetanus combined vaccine.
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