Table 1 Baseline characteristics and endpoints of the study participants

From: A large language model for clinical outcome adjudication from telephone follow-up interviews: a secondary analysis of a multicenter randomized clinical trial

Variables

Overall

(n = 1022)

JL center (n = 307)

NFH center (n = 345)

JNU center (n = 370)

Demographics

    

 Female, no (%)

403 (39.4)

106 (34.5)

135 (39.1)

162 (43.8)

 Male, no (%)

619 (60.6)

201 (65.5)

210 (60.9)

208 (56.2)

 Age, mean ± SD (years)

63.1 (11.0)

64.0 (11.3)

62.7 (10.6)

62.7 (11.1)

 BMI, mean ± SD (kg/m2)

24.8 (3.6)

24.4 (3.2)

24.9 (3.3)

25.1 (4.0)

Cardiac risk factors, no (%)

    

 Hypertension

599 (58.6)

201 (65.5)

209 (60.6)

189 (51.1)

 Diabetes

235 (23.0)

76 (24.8)

94 (27.2)

65 (17.6)

 Dyslipidemia

222 (21.7)

75 (24.4)

77 (22.3)

70 (18.9)

 Smoking

167 (16.3)

59 (19.2)

38 (11.0)

70 (18.9)

 Family history of CAD

65 (6.4)

51 (16.6)

5 (1.4)

9 (2.4)

Symptoms, no (%)

    

 Chest pain

253 (24.8)

85 (27.7)

106 (30.7)

62 (16.8)

 Chest stuffiness

365 (35.7)

107 (34.9)

141 (40.9)

117 (31.6)

 Dyspnea

103 (10.1)

36 (11.7)

31 (9.0)

36 (9.7)

 Others (palpitation, syncope, etc.)

204 (20.0)

55 (17.9)

80 (23.2)

69 (18.6)

 Asymptomatic

350 (34.2)

105 (34.2)

89 (25.8)

156 (42.2)

Degree of stenosis on CCTA, no (%)

    

 CAD-RADS 2

437 (42.9)

108 (35.4)

144 (41.7)

185 (50.1)

 CAD-RADS 3

296 (29.0)

99 (32.5)

107 (31.0)

90 (24.4)

 CAD-RADS 4

286 (28.1)

98 (32.1)

94 (27.2)

94 (25.5)

Group assignment, no (%)

    

 CCTA + CT-FFR

524 (51.3)

155 (50.5)

170 (49.3)

199 (53.8)

 CCTA alone

498 (48.7)

152 (49.5)

175 (50.7)

171 (46.2)

Recording files

    

 Number of recording files, no (%)

1046 (100)

321 (30.7)

355 (33.9)

370 (35.4)

 Duration of the recording (median (IQR), sec)

147 (96–216)

178 (127–258.5)

177 (128–252)

93 (63–136)

 Length of the text (median (IQR), words)

587.5 (362.8–865.5)

713.0 (539.5–1034)

750 (557–982)

317.5 (238.0–499.5)

Outcomesa, no (%)

    

 1-year ICA

112 (11.0)

45 (14.7)

47 (13.7)

20 (5.4)

 1-year revascularization

92 (9.0)

36 (11.7)

40 (11.6)

16 (4.3)

 PCI

82 (8.0)

35 (11.4)

35 (10.2)

12 (3.2)

 CABG

10 (1.0)

1 (0.3)

5 (1.5)

4 (1.1)

1-year MACE

    

 All cause death

22 (2.2)

11 (3.6)

3 (0.9)

8 (2.2)

 Cardiac

3 (0.3)

1 (0.3)

2 (0.6)

0

 Noncardiac

16 (1.6)

9 (2.9)

1 (0.3)

6 (1.6)

 Unknown

3 (0.3)

1 (0.3)

0

2 (0.5)

 Nonfatal acute MI

5 (0.5)

3 (1.0)

1 (0.3)

1 (0.3)

 Urgent revascularization

3 (0.3)

0

3 (0.8)

0

  1. BMI body mass index, CABG coronary artery bypass grafting; CAD coronary artery disease; CAD-RADS coronary artery disease-reporting and data system; CCTA coronary CT angiography; CT-FFR CT derived fractional flow reserve; JL Jinling Hospital; JNU the affiliated hospital of Jining Medical University; ICA invasive coronary angiography; MACE major adverse cardiovascular event; MI, myocardial infarction; NFH Nanjing First Hospital; PCI percutaneous coronary intervention; SD standard deviation.
  2. aThe outcomes were adjudicated by an independently clinical events committee with referring to medical records (admission note or discharge summary at minimum), referred as golden reference standards.
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