Fig. 4: Autoantibodies targeting G protein-coupled receptors. | Nature Communications

Fig. 4: Autoantibodies targeting G protein-coupled receptors.

From: Autoantibody landscape and functional role of anti-C-C motif chemokine receptor 8 autoantibodies in systemic sclerosis: post-hoc analysis of a B-cell depletion trial

Fig. 4

A Serum levels of autoantibodies targeting G protein-coupled receptors (GPCRs) of clinical relevance by treatment arm (HC: n = 45, placebo week 0: n = 21, placebo week 24: n = 21, RTX HR week 0: n = 11, RTX HR week 24: n = 11, RTX LR week 0: n = 13, RTX LR week 24: n = 13). B The heatmap illustrates correlation between the autoantibodies targeting GPCRs and clinical traits of SSc. *: P < 0.05, **: P < 0.01, ***: P < 0.001. P values were calculated by Spearman’s correlation test.

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