Fig. 1: Divergent outcomes in seronegative adults inoculated with SARS-CoV-2.

a Schematic of the study timeline and sample collection timepoints utilised for this analysis. b Diagram of the infection outcome groups and subgroups, and the associated viral loads measured in daily nose and throat swabs by qPCR (log10 N gene copies/ml); viral load data was published previously2. Images created in BioRender. Wagstaffe, H. (2025) https://BioRender.com/nqvesc4, https://BioRender.com/hh208ml.