Fig. 5: miR-71 coordinates muscle-glia cell-non-autonomous stress signaling. | Nature Communications

Fig. 5: miR-71 coordinates muscle-glia cell-non-autonomous stress signaling.

From: The microRNA miR-71 suppresses maladaptive UPRmt signaling through both cell-autonomous and cell-non-autonomous mechanisms

Fig. 5

a representative photomicrographs of animals (outlined by a white dashed line) expressing dve-1p::DVE-1::GFP. Red arrow indicates GFP signal in head cells. Yellow arrow indicates GFP signal in posterior intestinal cells. Scale bar, 50 μm. b representative photomicrographs of the heads of animals (outlined by a white dashed line) expressing the glial reporter mir-228p::mKate2 and dve-1p::DVE-1::GFP. Scale bar, 20 μm. Yellow boxes correspond to enlarged images displayed on the right side that show a close-up of glial cells. Scale bar, 10 μm. c−h, (c), (e) and (g) representative photomicrographs of the heads of animals (outlined by a white dashed line) expressing dve-1p::DVE-1::GFP. Scale bar, 20 μm. d−h quantification of GFP fluorescence intensity. Columns represent mean ± SEM; for d n = 11, for f, n = 59, 64, 55 and 41, for h, n = 20; one-way ANOVA with Tukey’s post hoc test. Source data are provided as a Source Data file.

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