Fig. 1: Impaired motor function in Fgf7−/− mice compared to wildtype mice.
From: FGF7 promotes load-bearing tendon regeneration and suppresses fibrosis
A Morphological changes and body length at postnatal days 7, 14, 21, and 10 weeks. Scale bars, 5 mm. B Statistical analysis of body length (left) and body weight (right) at postnatal days 7, 14, 21, and 10 weeks for Fgf7−/− and wildtype mice (n = 8 per time point, independent experiments, bars represent mean ± SD; NS: not significant, two-tailed Student’s t test. body length: 7 days: t = 1.075, df = 14; 14 days: t = 0.5283, df = 14; 21 days: t = 0.7001, df = 3; 10 weeks: t = 1.134, df = 3. Body weight: 7 days: t = 0.5048, df = 14; 14 days: t = 0.1722, df = 12; 21 days: t = 1.265, df = 3; 10 weeks: t = 0.3482, df = 14.). C Schematic representation of the wire hang test protocol. D Statistical analysis of hanging time in the wire hang test at postnatal days 7, 14, 21, and 10 weeks for Fgf7−/− and wildtype mice (n = 8 per time point, independent experiments, bars represent mean ± SD; WT wildtype. NS: not significant, *p < 0.05, **p < 0.01, two-tailed Student’s t test. Hanging time in the wire hang test at postnatal days: 7 days: t = 0.409, df = 14; 14 days: t = 0.06817, df = 14; 21 days: t = 3.399, df = 14; 10 weeks: t = 5.913, df = 14.). E Schematic representation of the treadmill test. F Statistical analysis of maximum running speed in the treadmill exhaustion test at postnatal day 21 and 10 weeks for Fgf7−/− and wildtype mice (n = 11 per time point, independent experiments, bars represent mean ± SD; WT wildtype. *p < 0.05, ***p < 0.001, two-tailed Student’s t test. Maximum running speed at postnatal days: 21 days: t = 9.478, df = 20; 10 weeks: t = 13.35, df = 20). G Statistical analysis of maximum running distance in the treadmill exhaustion test at postnatal day 21 and 10 weeks for Fgf7−/− and wildtype mice (n = 11 per time point, independent experiments, bars represent mean ± SD; WT wildtype. *p < 0.05, ***p < 0.001, two-tailed Student’s t test. Maximum running distance at postnatal days: 21 days: t = 10, df = 20; 10 weeks: t = 13.92, df = 20). H Statistical analysis of maximum running time in the treadmill exhaustion test at postnatal day 21 and 10 weeks for Fgf7−/− and wildtype mice (n = 11 per time point, independent experiments, bars represent mean ± SD; WT wildtype. *p < 0.05, ***p < 0.001, two-tailed Student’s t test. Maximum running time at postnatal days: 21 days: t = 9.223, df = 20; 10 weeks: t = 13.23, df = 20). Source data are provided as a Source Data file.
